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Agriculture is the most important sector for the economy of Ghana, and for its continued growth, the use and management of agricultural inputs, such as pesticides, had to be improved. Since 2009, obsolete pesticides have been stored in the temporary storage facility at the Plant Protection and Regulatory Services Directorate office, close to a water body that provides water for the surrounding communities. The poor storage of stockpiles posed a severe risk to people’s health and the environment. Therefore, this project was implemented to dispose of the hazardous chemicals and build the institutional capacity to manage them in the future, in order to strengthen the agricultural sector in Ghana and improve food security.